Selamat kepada Ibu Afiahayati yang tergabung dalam tim NGS COVID-19 UGM. Tim telah mempublikasikan paper berjudul ”Full-length genome characterization and phylogenetic analysis of SARS-CoV-2 virus strains from Yogyakarta and Central Java, Indonesia ” pada PeerJ Journal (Scopus Q1, Impact Factor:2,8).

Pada paper ini, dipaparkan terkait karakterisktik dan analisis filogenetik Virus Sars-Cov-2 dari sample pasien di Yogyakarta dan Jawa Tengah, juga ditemukan beberapa mutasi diantaranya D614G yang memiliki daya infeksi 10 kali lebih tinggi. Pada penelitian ini, peran bioinformatika sangat penting diantaranya untuk melakukan assembly, alignment, konstruksi dan analisis filogenetik serta menemukan mutasi dari virus. read more

Selamat kepada Bu Binti Solihah (Mahasiswa S3 Ilmu Komputer), Pak Dr. Azhari dan Bu Aina Musdholifah, Ph.D. yang telah mempublikasikan paper berjudul “Enhancement of conformational B-cell
epitope prediction using CluSMOTE”. Paper dipublikasikan pada international journal PeerJ Computer Science (Scopus Q1).

Enhancement of conformational B-cell epitope prediction using CluSMOTE

Background
A conformational B-cell epitope is one of the main components of vaccine design. It contains separate segments in its sequence, which are spatially close in the antigen chain. The availability of Ag-Ab complex data on the Protein Data Bank allows for the development predictive methods. Several epitope prediction models also have been developed, including learning-based methods. However, the performance of the model is still not optimum. The main problem in learning-based prediction models is class imbalance. read more